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Article

Colorectal cancer-associated mutations impair EphB1 kinase function.

The Journal of biological chemistry - 1 Sept 2023

Kim Yunyoung, Ahmed Sultan, Miller W Todd

Abstract excerpt

Erythropoietin-producing hepatoma (Eph) receptor tyrosine kinases regulate the migration and adhesion of cells that are required for many developmental processes and adult tissue homeostasis. In the intestinal epithelium, Eph signaling controls the positioning of cell types along the crypt-villus axis. Eph activity can suppress the progression of colorectal cancer (CRC). The most frequently mutated Eph receptor...

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Identifiers

PMID: 37527777
DOI: 10.1016/j.jbc.2023.105115
PMCID: PMC10463257

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Colorectal cancer-associated mutations impair EphB1 kinase function.PMID 37527777Read ↗

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