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Article

EphA3 promotes malignant transformation of colorectal epithelial cells by upregulating oncogenic pathways.

Cancer letters - 28 Dec 2016

Li Mingqi, Yang Cheng, Liu Xin, Yuan Liang, Zhang Fubin, Wang Muhong, Miao Dazhuang, Gu Xinyue, Jiang Shixiong, Cui Binbin, Tong Jinxue, Yu Zhiwei

Abstract excerpt

Ephrin Type-A Receptor 3 (EphA3) belongs to the ephrin receptor subfamily of the protein tyrosine kinase family, and plays an important role in embryogenesis and neurogenesis. This study aimed to investigate the role of EphA3 in promoting malignant transformation of colorectal epithelial cells, and explore underlying molecular mechanisms. Colorectal cancer tissue specimens from 68 patients were analyzed for EphA3...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27721017
DOI: 10.1016/j.canlet.2016.10.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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