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Article

Germline EPHB2 receptor variants in familial colorectal cancer.

PloS one - 6 Aug 2008

Zogopoulos George, Jorgensen Claus, Bacani Julinor, Montpetit Alexandre, Lepage Pierre, Ferretti Vincent, Chad Lauren, Selvarajah Subani, Zanke Brent, Hudson Thomas J, Pawson Tony, Gallinger Steven

Abstract excerpt

Familial clustering of colorectal cancer occurs in 15-20% of cases, however recognized cancer syndromes explain only a small fraction of this disease. Thus, the genetic basis for the majority of hereditary colorectal cancer remains unknown. EPHB2 has recently been implicated as a candidate tumor suppressor gene in colorectal cancer. The aim of this study was to evaluate the contribution of EPHB2 to hereditary...

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Share to Adenomatous Polyposis Coli
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms, Hereditary Nonpolyposis

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Source

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Identifiers

PMID: 18682749
DOI: 10.1371/journal.pone.0002885
PMCID: PMC2483346

Genes

EPHB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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