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The transcriptional landscape and diagnostic potential of long non-coding RNAs in esophageal squamous cell carcinoma

26 Jun 2023

Abstract excerpt

Esophageal squamous cell carcinoma (ESCC) is a deadly cancer with no clinically relevant biomarkers for early detection. Here, we comprehensively characterized the transcriptional landscape of long non-coding RNAs (lncRNAs) in paired tumor and normal tissue specimens from 93 ESCC patients, and identified six key malignancy-specific lncRNAs that were integrated into a Multi-LncRNA Malignancy Risk Probability model...

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PMID: 37365153
DOI: 10.1038/s41467-023-39530-1

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