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Joint analysis of human retroelements-linked histone modification profiles reveals quickly evolving molecular processes connected with cancer

2025-09-27

Abstract excerpt

<h4>ABSTRACT</h4> Human retroelements (REs), which comprise approximately 40% of the genome, have played a pivotal role in the evolution of key molecular processes, such as placental development, by introducing novel regulatory elements near host gene promoters and enhancers. Despite their genomic abundance and regulatory influence, the functional trajectories of REs remain poorly understood. Here, leveraging ChI...

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Literature Corpus work
07ad7176-e3ac-5059-b6ab-56d7cb2d69d2
DOI
10.1101/2025.09.24.677146
Open publication

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Joint analysis of human retroelements-linked histone modification profiles reveals quickly evolving molecular processes connected with cancerDOI 10.1101/2025.09.24.677146
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