Article
Genome engineering by transgene-instructed gene conversion in C. elegans.
Methods in cell biology - 1 Jan 2011
Robert Valérie J P, Bessereau Jean-Louis
Abstract excerpt
The nematode Caenorhabditis elegans is an anatomically simple metazoan that has been used over the last 40 years to address an extremely wide range of biological questions. One major advantage of the C. elegans system is the possibility to conduct large-scale genetic screens on randomly mutagenized animals, either looking for a phenotype of interest and subsequently relate the mutated gene to the biological...
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