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Article

Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences.

The EMBO journal - 1 Dec 1991

Mello C C, Kramer J M, Stinchcomb D, Ambros V

Abstract excerpt

We describe a dominant behavioral marker, rol-6(su-1006), and an efficient microinjection procedure which facilitate the recovery of Caenorhabditis elegans transformants. We use these tools to study the mechanism of C.elegans DNA transformation. By injecting mixtures of genetically marked DNA molecules, we show that large extrachromosomal arrays assemble directly from the injected molecules and that homologous...

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Identifiers

PMID: 1935914
DOI: 10.1002/j.1460-2075.1991.tb04966.x
PMCID: PMC453137

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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