Article
Clinical isolates of hepatitis B virus genotype C have higher in vitro transmission efficiency than genotype B isolates.
Journal of medical virology - 1 Jun 2023
Li Jing, Li Jisu, Chen Shiqi, Xu Weicheng, Zhang Jiming, Tong Shuping
Abstract excerpt
Serum samples were collected from 54 hepatitis B e antigen (HBeAg)-positive Chinese patients infected with hepatitis B virus (HBV) subgenotype B2 or C2. They were compared for transmission efficiency using same volume of samples or infectivity using same genome copy number. Adding polyethylene glycol (PEG) during inoculation did not increase infectivity of fresh samples but markedly increased infectivity...
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