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Article

Replication efficiency and sequence analysis of full-length hepatitis B virus isolates from hepatocellular carcinoma tissues.

International journal of cancer - 10 Dec 2002

Lin Xu, Ma Zhang-Mei, Yao Xin, Zhang Yan-Ping, Wen Yu-Mei

Abstract excerpt

Prolonged replication of hepatitis B virus (HBV) in liver tissues of hepatitis B patients has been considered as an important risk factor for the development of malignancy. Few studies on full-length HBV sequencing in association with the replication efficiency of isolates from HCC tissues have been reported. To study the structural and functional genomics of HBV isolates from Chinese hepatocellular carcinoma...

Topics

Base Sequence
Carcinoma, Hepatocellular
Cells, Cultured
DNA, Viral
Enhancer Elements, Genetic
Genome, Viral
Genotype
Hepatitis B Core Antigens
Hepatitis B Surface Antigens
Hepatitis B virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Liver Neoplasms

Molecular Sequence Data

Mutation

Promoter Regions, Genetic

Sequence Homology, Amino Acid

Transfection

Virus Replication

Source

Identifiers

PMID: 12432551
DOI: 10.1002/ijc.10733

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-12432551-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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