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Efficient cell culture systems for hepatitis E virus strains in feces and circulating blood

1 Jan 2011

Abstract excerpt

Attempts have been made to propagate hepatitis E virus (HEV) in primary hepatocyte culture and various other cultured cells. However, the replication ability of HEV recovered from culture media remains extremely low. Recently, efficient culture systems have been established in PLC/PRF/5 (hepatocellular carcinoma) and A549 (lung cancer) cell lines for HEV strains of genotypes 3 and 4 in our laboratory. They...

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Share to Hepatitis Viruses Studies and Epidemiology
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PMID: 21294213
DOI: 10.1002/rmv.678

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