Article
Mechanism of the dependence of hepatitis B virus genotype G on co-infection with other genotypes for viral replication.
Journal of viral hepatitis - 1 Apr 2013
Sakamoto T, Tanaka Y, Watanabe T, Iijima S, Kani S, Sugiyama M, Murakami S, Matsuura K, Kusakabe A, Shinkai N, Sugauchi F, Mizokami M
Abstract excerpt
Hepatitis B virus (HBV) is classified into several genotypes. Genotype G (HBV/G) is characterised by worldwide dispersion, low intragenotypic diversity and a peculiar sequence of the precore and core region (stop codon and 36-nucleotide insertion). As a rule, HBV/G is detected in co-infection with another genotype, most frequently HBV/A2. In a previous in vivo study, viral replication of HBV/G was significantly...
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