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Article

The Hepatitis B Virus Genotype Affects the Persistence of Viral Replication in Immunodeficient NOG Mice.

PloS one - 1 Jan 2015

Yokoyama Yoshinobu, Miyagi Takuya, Hikita Hayato, Yoshioka Teppei, Mukai Kaori, Nawa Takatoshi, Sakamori Ryotaro, Ohkawa Kazuyoshi, Hiramatsu Naoki, Takahashi Takeshi, Suemizu Hiroshi, Ryo Akihide, Tatsumi Tomohide, Takehara Tetsuo

Abstract excerpt

BACKGROUND & AIMS: At least eight genotypes of Hepatitis B virus (HBV) have been identified. HBV genotype C is the most common genotype in Japan, although the incidence of HBV genotype A is increasing. The reason underlying the differences in viral multiplication of the HBV genotypes is unclear, especially in vivo. The purpose of this study was to elucidate the differences in HBV load and the persistence of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26658490
DOI: 10.1371/journal.pone.0144775
PMCID: PMC4682774

Genes

NOG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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