Article
Identifying genetic loci and phenomic associations of substance use traits: A multi-trait analysis of GWAS (MTAG) study.
Addiction (Abingdon, England) - 1 Oct 2023
Xu Heng, Toikumo Sylvanus, Crist Richard C, Glogowska Klaudia, Jinwala Zeal, Deak Joseph D, Justice Amy C, Gelernter Joel, Johnson Emma C, Kranzler Henry R, Kember Rachel L
Abstract excerpt
BACKGROUND AND AIMS: Genome-wide association studies (GWAS) of opioid use disorder (OUD) and cannabis use disorder (CUD) have lagged behind those of alcohol use disorder (AUD) and smoking, where many more loci have been identified. We sought to identify novel loci for substance use traits (SUTs) in both African- (AFR) and European- (EUR) ancestry individuals to enhance our understanding of the traits' genetic...
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