Article

Genetic liability for substance use associated with medical comorbidities in electronic health records of African- and European-ancestry individuals

2021-04-22

Abstract excerpt

Polygenic risk scores (PRS) represent an individual’s summed genetic risk for a trait and can serve as biomarkers for disease. Less is known about the utility of PRS as a means to quantify genetic risk for substance use disorders (SUDs) than for many other traits. Nonetheless, the growth of large, electronic health record-based biobanks makes it possible to evaluate the association of SUD PRS with other traits. We...

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Literature Corpus work: 894cde88-932d-5850-856b-db8667a6da3f
DOI: 10.1101/2021.04.19.21255619

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