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Article

Genome-wide association analysis of opioid use disorder: A novel approach using clinical data.

Drug and alcohol dependence - 1 Dec 2020

Song Wenyu, Kossowsky Joe, Torous John, Chen Chia-Yen, Huang Hailiang, Mukamal Kenneth J, Berde Charles B, Bates David W, Wright Adam

Abstract excerpt

BACKGROUND: Opioid use disorder (OUD) represents a large and pervasive global public health challenge. Previous genetic studies have demonstrated the significant heritability of OUD and identified several single-nucleotide polymorphisms (SNPs) associated with its prevalence. METHODS: In this paper, we conducted a genome-wide association analysis on opioid use disorder that leveraged genetic and clinical data...

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Identifiers

PMID: 32961455
DOI: 10.1016/j.drugalcdep.2020.108276
PMCID: PMC7736461

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