Article
High-resolution melting assay for rapid, simultaneous detection of JAK2, MPL and CALR variants.
Journal of clinical pathology - 16 Aug 2024
Sande Christopher M, Yang Guang, Mohamed Ayman, Legendre Ben L, Pion Danielle, Ferro Stephanie L, Grimm Kate, Elenitoba-Johnson Kojo S J
Abstract excerpt
AIMS: Identification of recurrent genetic alterations in JAK2, MPL and CALR remains crucial in the diagnosis of Philadelphia-negative myeloproliferative neoplasms (MPNs). Current laboratory testing algorithms may entail batching and/or sequential testing, involving multiple testing modalities and sometimes send-out testing that increase the technical and economic demands on laboratories while delaying patient...
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