Article
Analysis of Molecular Testing for Suspected Myeloproliferative Neoplasm at a Hybrid Community-Academic Health System.
The Journal of molecular diagnostics : JMD - 1 Jan 2025
Stone Andrew B, Martinez Ryan J, Arries Cade, Nelson Andrew C, Thyagarajan Bharat, Yohe Sophia, Mroz Pawel
Abstract excerpt
Testing for somatic mutations in JAK2, MPL, and CALR genes is critical in the diagnosis of myeloproliferative neoplasms (MPNs). However, this testing may have inadvertently led to increased requests to rule out MPN, including clinical situations with low pretest probability. This article examines JAK2, MPL, and CALR testing by next-generation sequencing (NGS) with the goal of formulating practical guidelines to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.