Article
Screening of somatic mutations in the JAK2 and CALR genes by high-resolution melting curve analysis.
Klinicheskaia laboratornaia diagnostika - 23 May 2021
Kurochkin D V, Maslyukova I E, Subbotina T N, Khazieva A S, Vasiliev E V, Mikhalev M A, Dunaeva E A, Mironov K O
Abstract excerpt
Somatic mutations associated with oncological diseases, including Ph-myeloproliferative neoplasms (Ph-MPN), are very diverse, occur with different frequencies and different allelic burden levels. Therefore, at the initial stage of performing molecular-genetic diagnostic procedures, it is desirable to be able to conduct screening tests in the laboratory. This is especially important when analyzing rare and diverse...
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