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Article

Metabolic Overlap between Alzheimer's Disease and Metabolic Syndrome Identifies the PVRL2 Gene as a New Modulator of Diabetic Dyslipidemia.

International journal of molecular sciences - 18 Apr 2023

Guardiola Montse, Muntané Gerard, Martínez Iris, Martorell Lourdes, Girona Josefa, Ibarretxe Daiana, Plana Núria, Bullido María J, Vilella Elisabet, Ribalta Josep

Abstract excerpt

BACKGROUND: Alzheimer's disease (AD) and type 2 diabetes mellitus (T2DM) share metabolic alterations such as abnormal insulin and lipid metabolism and have some common genetic factors such as APOE genotype. Taking this into account, we hypothesized that we could identify common genetic factors involved in the development of diabetes and cardiovascular diseases. METHODOLOGY: We first genotyped 48 single nucleotide...

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Identifiers

PMID: 37108578
DOI: 10.3390/ijms24087415
PMCID: PMC10139078

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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