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Article

Multi-trait association studies discover pleiotropic loci between Alzheimer’s disease and cardiometabolic traits

2020-09-01

Abstract excerpt

Identification of genetic risk factors that are shared between Alzheimer’s disease (AD) and other traits, i.e., pleiotropy, can help improve our understanding of the etiology of AD and potentially detect new therapeutic targets. Motivated by previous epidemiological correlations observed between cardiometabolic traits and AD, we performed a set of bivariate genome-wide association studies coupled with colocalizati...

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Literature Corpus work
47b51674-dfaf-5314-9a3e-8fbc3e926955
DOI
10.1101/2020.08.26.20179366
Open publication

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Multi-trait association studies discover pleiotropic loci between Alzheimer’s disease and cardiometabolic traitsDOI 10.1101/2020.08.26.20179366
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