Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Insulin resistance in Alzheimer’s disease: The genetics and metabolomics links

22 Dec 2022

Abstract excerpt

Alzheimer's disease (AD) is a neurodegenerative disease with significant socioeconomic burden worldwide. Although genetics and environmental factors play a role, AD is highly associated with insulin resistance (IR) disorders such as metabolic syndrome (MS), obesity, and type two diabetes mellitus (T2DM). These findings highlight a shared pathogenesis. The use of metabolomics as a downstream systems' biology...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diet and metabolism studies
Share to Diet, Metabolism, and Disease
Share to Metabolomics and Mass Spectrometry Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36566957
DOI: 10.1016/j.cca.2022.12.016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Insulin resistance in Alzheimer’s disease: The genetics and metabolomics linksPMID 36566957Read ↗

Molecular landscape of the overlap between Alzheimer’s disease and somatic insulin-related diseasesSemantic proximity Read ↗

Insulin Resistance and Metabolic Comorbidities in Alzheimer’s DiseaseSemantic proximity Read ↗

Integrative metabolomics science in Alzheimer’s disease: Relevance and future perspectivesSemantic proximity Read ↗

Spotlight on the Pathophysiological Trajectories Linked to Alzheimer’s Disease (AD): Blood-Brain Barrier (BBB); Neuroinflammation; APOE4 Allele and AD- Insulin Resistance (IR) Pathogenic LinkSemantic proximity Read ↗

Alzheimer’s Disease and Type 2 Diabetes Relationships. I. Cellular and Molecular Common Pathological MechanismsSemantic proximity Read ↗

Navigation Between Alzheimer’s Disease (AD) and Its Various Pathophysiological Trajectories: The Pathogenic Link to Neuroimmunology—Genetics and NeuroinflammationSemantic proximity Read ↗

Integrative metabolomics‐genomics approach reveals key metabolic pathways and regulators of Alzheimer's diseaseSemantic proximity Read ↗

Advancements in multi-omics research to address challenges in Alzheimer’s disease: a systems biology approach utilizing molecular biomarkers and innovative strategiesSemantic proximity Read ↗

Integrated analysis of genomics, longitudinal metabolomics, and Alzheimer's risk factors among 1,111 cohort participantsSemantic proximity Read ↗

Insulin Resistance as a Link between Amyloid-Beta and Tau Pathologies in Alzheimer’s DiseaseSemantic proximity Read ↗

Alteration of Metabolic Profile During the Progression of Alzheimer’s DiseaseSemantic proximity Read ↗

Distinct metabolic signatures of Alzheimer's and Parkinson's disease revealed through genetic overlap.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.