Article

Distinct metabolic signatures of Alzheimer’s and Parkinson’s disease revealed through genetic overlap with metabolic markers

2025-07-31

Abstract excerpt

<h4>ABSTRACT</h4> Metabolic dysfunction is increasingly implicated in neurodegenerative diseases, yet the genetic architecture linking metabolic markers with Alzheimer’s disease (AD) and Parkinson’s disease (PD) remains unclear. We systematically analysed phenotypic and genetic relationships between 249 circulating metabolites with AD and PD, comparing patterns to body mass index (BMI), type 2 diabetes (T2D), cor...

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Literature Corpus work: 0e98a559-161b-57a5-bb5b-c6dc4c3eb3d0
DOI: 10.1101/2025.07.31.25332114

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