Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Variants of Lipoprotein Lipase and Regulatory Factors Associated with Alzheimer's Disease Risk.

International journal of molecular sciences - 6 Nov 2020

D Bruce Kimberley, Tang Maoping, Reigan Philip, H Eckel Robert

Abstract excerpt

Lipoprotein lipase (LPL) is a key enzyme in lipid and lipoprotein metabolism. The canonical role of LPL involves the hydrolysis of triglyceride-rich lipoproteins for the provision of FFAs to metabolic tissues. However, LPL may also contribute to lipoprotein uptake by acting as a molecular bridge between lipoproteins and cell surface receptors. Recent studies have shown that LPL is abundantly expressed in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Amyloid beta-Peptides

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lipoprotein Lipase

Share to Lipoproteins

Share to Macrophages

Share to Microglia

Share to Structure-Activity Relationship

Share to Triglycerides

Source

Open in PubMed Open full text

Identifiers

PMID: 33172164
DOI: 10.3390/ijms21218338
PMCID: PMC7664401

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Variants of Lipoprotein Lipase and Regulatory Factors Associated with Alzheimer's Disease Risk.PMID 33172164Read ↗

Lipoprotein lipase mutations and Alzheimer's disease.Semantic proximity Read ↗

Roles for lipoprotein lipase in Alzheimer's disease: an association study.Semantic proximity Read ↗

A polymorphism in lipoprotein lipase affects the severity of Alzheimer's disease pathophysiology.Semantic proximity Read ↗

Lipoprotein lipase: genetics, lipid uptake, and regulation.Semantic proximity Read ↗

Lipoprotein lipase gene sequencing and plasma lipid profile.Semantic proximity Read ↗

Lipoprotein Lipase: Structure, Function, and Genetic VariationSemantic proximity Read ↗

Lipoprotein Lipase: Structure, Function, and Genetic VariationSemantic proximity Read ↗

Apolipoprotein E in lipid metabolism and neurodegenerative disease.Semantic proximity Read ↗

Lipoprotein lipase gene polymorphism rs1059611 functionally influences serum lipid concentrations.Semantic proximity Read ↗

Lipoprotein lipase: physiology, biochemistry, and molecular biology.Semantic proximity Read ↗

<i>PLCG2</i> as a Risk Factor for Alzheimer’s DiseaseSemantic proximity Read ↗

Coronary Artery Disease-Associated LIPA Coding Variant rs1051338 Reduces Lysosomal Acid Lipase Levels and Activity in Lysosomes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.