Article
A suggested shared aetiology of dementia - a colocalization study.
Neurobiology of aging - 1 Sept 2022
Yu Xinzhu, Lophatananon Artitaya, Mekli Krisztina, Burns Alistair, Muir Kenneth R, Guo Hui
Abstract excerpt
Identification of shared causal genes between dementia and its related clinical outcomes can help understand shared aetiology and multimorbidity surrounding dementia. We performed the HyPrColoc colocalization analysis to detect possible shared causal genes between dementia or Alzheimer's disease (AD) and 5 selected traits: stroke, diabetes, atherosclerosis, cholesterol level, and alcohol consumption within 601...
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