Article
Effect of polygenic risk score, family load of schizophrenia and exposome risk score, and their interactions, on the long-term outcome of first-episode psychosis.
Psychological medicine - 1 Oct 2023
Cuesta M J, Papiol S, Ibañez B, García de Jalón E, Sánchez-Torres A M, Gil-Berrozpe G J, Moreno-Izco L, Zarzuela A, Fañanás L, Peralta V
Abstract excerpt
BACKGROUND: Consistent evidence supports the involvement of genetic and environmental factors, and their interactions, in the etiology of psychosis. First-episode psychosis (FEP) comprises a group of disorders that show great clinical and long-term outcome heterogeneity, and the extent to which genetic, familial and environmental factors account for predicting the long-term outcome in FEP patients remains...
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