Article
The emerging molecular architecture of schizophrenia, polygenic risk scores and the clinical implications for GxE research.
Social psychiatry and psychiatric epidemiology - 1 Feb 2014
Iyegbe Conrad, Campbell Desmond, Butler Amy, Ajnakina Olesya, Sham Pak
Abstract excerpt
Schizophrenia is a devastating mental disorder. The level of risk in the general population is sustained by the persistence of social, environmental and biological factors, as well as their interactions. Socio-environmental risk factors for schizophrenia are well established and robust. The same can belatedly be said of genetic risk factors for the disorder. Recent progress in schizophrenia genetics is primarily...
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