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Article

The "polyenviromic risk score": Aggregating environmental risk factors predicts conversion to psychosis in familial high-risk subjects.

Schizophrenia research - 1 Mar 2017

Padmanabhan Jaya L, Shah Jai L, Tandon Neeraj, Keshavan Matcheri S

Abstract excerpt

BACKGROUND: Young relatives of individuals with schizophrenia (i.e. youth at familial high-risk, FHR) are at increased risk of developing psychotic disorders, and show higher rates of psychiatric symptoms, cognitive and neurobiological abnormalities than non-relatives. It is not known whether overall exposure to environmental risk factors increases risk of conversion to psychosis in FHR subjects. METHODS:...

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PMID: 28029515
DOI: 10.1016/j.schres.2016.10.014
PMCID: PMC5365360

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