Article
Modelling gene-environment interaction in first episodes of psychosis.
Schizophrenia research - 1 Nov 2017
Bernardo Miguel, Bioque Miquel, Cabrera Bibiana, Lobo Antonio, González-Pinto Ana, Pina Laura, Corripio Iluminada, Sanjuán Julio, Mané Anna, Castro-Fornieles Josefina, Vieta Eduard, Arango Celso, Mezquida Gisela, Gassó Patricia, Parellada Mara, Saiz-Ruiz Jerónimo, Cuesta Manuel J, Mas Sergi
Abstract excerpt
INTRODUCTION: Recent research demonstrates the heterogeneous etiology of psychotic disorders, where gen-environment (GxE) interaction plays a key role. Large genetic studies have linked many genetic variants with schizophrenia, but each variant is only associated with a small effect and the GxE interaction contribution has not been evaluated. METHODS: The PEPs Project was designed to carefully collect a large...
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