Article
Structural analysis and conformational dynamics of SOCS1 gene mutations involved in diffuse large B-cell lymphoma.
Gene - 15 May 2023
Dristy Tamanna Tasnim, Noor Al-Rownoka, Dey Puja, Saha Ayan
Abstract excerpt
OBJECTIVES: The SOCS1 gene is frequently mutated in primary Diffuse Large B-Cell Lymphoma (DLBCL) patients and is associated with a reduced survival rate. Using various computational techniques, the current study aims to identify Single Nucleotide Polymorphisms (SNPs) in the SOCS1 gene that are associated with the mortality rate of DLBCL patients. This study also evaluates the effects of SNPs on the structural...
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