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Article

SOCS1 mutation subtypes predict divergent outcomes in diffuse large B-Cell lymphoma (DLBCL) patients.

Oncotarget - 1 Jan 2013

Schif Birgit, Lennerz Jochen K, Kohler Christian W, Bentink Stefan, Kreuz Markus, Melzner Ingo, Ritz Olga, Trümper Lorenz, Loeffler Markus, Spang Rainer, Möller Peter

Abstract excerpt

Suppressor of cytokine signaling 1 (SOCS1) is frequently mutated in primary mediastinal and diffuse large B-cell lymphomas (DLBCL). Currently, the prognostic relevance of these mutations in DLBCL is unknown. To evaluate the value of the SOCS1 mutation status as a prognostic biomarker in DLBCL patients, we performed full-length SOCS1 sequencing in tumors of 154 comprehensively characterized DLBCL patients. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Lymphoma, Large B-Cell, Diffuse

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Source

Open in PubMed Open full text

Identifiers

PMID: 23296022
DOI: 10.18632/oncotarget.774
PMCID: PMC3702206

Genes

SOCS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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