Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SOCS2: physiological and pathological functions.

Frontiers in bioscience (Elite edition) - 1 Jan 2016

Letellier Elisabeth, Haan Serge

Abstract excerpt

Suppressors of cytokine signalling (SOCS) proteins are modulators of cytokine and growth factor signalling whose aberrant regulation has been linked to a variety of inflammatory and neoplastic diseases. SOCS proteins are able to act as substrate-recruiting component of E3-ubiquitin ligase complexes and target interacting proteins for degradation. At least some of the family members can also directly inhibit...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Central Nervous System
Share to SOCS1 gene
Share to SOCS3 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immune System

Share to Neoplasms

Share to Polymorphism, Single Nucleotide

Share to Structure-Activity Relationship

Share to Suppressor of Cytokine Signaling Proteins

Source

Identifiers

PMID: 26709655
DOI: 10.2741/E760

Genes

SOCS2
SOCS1
SOCS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SOCS2: physiological and pathological functions.PMID 26709655Read ↗

SOCS2 physiological and pathological functionsSemantic proximity Read ↗

Unravelling the druggability and immunological roles of the SOCS-family proteinsSemantic proximity Read ↗

SOCS: suppressors of cytokine signalling.Semantic proximity Read ↗

SOCS, inflammation, and cancerSemantic proximity Read ↗

SOCS1: a potent and multifaceted regulator of cytokines and cell‐mediated inflammationSemantic proximity Read ↗

SOCS Proteins in Immunity, Inflammatory Diseases, and Immune-Related CancerSemantic proximity Read ↗

Emerging roles of suppressor of cytokine signaling 3 in human cancersSemantic proximity Read ↗

SOCS, Inflammation, and AutoimmunitySemantic proximity Read ↗

SOCS3Semantic proximity Read ↗

Therapeutic Implication of SOCS1 Modulation in the Treatment of Autoimmunity and CancerSemantic proximity Read ↗

Role of SOCS1 in tumor progression and therapeutic applicationSemantic proximity Read ↗

Suppressors of Cytokine Signaling (SOCS) Proteins and JAK/STAT PathwaysSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.