Article
[SOCSJ gene mutations in patients with diffuse large B-cell lymphoma].
Terapevticheskii arkhiv - 1 Jan 2015
Gavrilina O A, Zvonkov E E, Biderman B V, Severina N A, Parovichnikova E N
Abstract excerpt
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous group of diseases, which accounts for 30% of all non-Hodgkin lymphomas. Current molecular studies have confirmed that there are several DLBCL subtypes characterized by different cellular origin, cytogenetic profile, molecular genetic disorders, and different pathogenesis. Impaired JAK-STAT signaling is a part of the pathogenesis of various cancers,...
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