Article
Integrated Multi-Omics Landscape of Liver Metastases.
Gastroenterology - 1 Mar 2023
Yang Shuai, Qian Ling, Li Zhixuan, Li Ye, Bai Jian, Zheng Bo, Chen Kun, Qiu Xinyao, Cai Guoxiang, Wang Shan, Huang Haiyan, Wu Jianmin, Zhu Yanjing, Zhangyang Qianwen, Feng Lanyun, Wu Tong, Wu Rui, Yang Airong, Wang Kaiting, Wang Ruiru, Zhang Yani, Zhao Yan, Wang Wenwen, Bao Jinxia, Shen Siyun, Hu Ji, Wu Xuan, Zhou Tao, Meng Zhiqiang, Liu Weiwei, Wang Hongyang, Wang Peng, Chen Lei
Abstract excerpt
BACKGROUND & AIMS: Lack of thorough knowledge about the complicated immune microenvironment (IM) within a variety of liver metastases (LMs) leads to inappropriate treatment and unsatisfactory prognosis. We aimed to characterize IM subtypes and investigate potential mechanisms in LMs. METHODS: Mass cytometry was applied to characterize immune landscape of a primary liver cancers and liver metastases cohort....
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