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A Single-Cell Atlas of Liver Metastases of Colorectal Cancer Reveals the Reprogramming of the Tumor Microenvironment in Response to Preoperative Chemotherapy

2020-10-09

Abstract excerpt

Metastasis is the primary cause of cancer-related mortality in colorectal cancer (CRC) patients. How to improve therapeutic options for patients with metastatic CRC (mCRC) is the core question for CRC treatment. However, the complexity and diversity of stromal context of the tumor microenvironment (TME) in liver metastases of CRC is not fully understood, and its influence on response to chemotherapy is unclear. He...

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Literature Corpus work
0e088d27-d760-5d42-a5cd-fcec93524c01
DOI
10.21203/rs.3.rs-84915/v1
Open publication

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A Single-Cell Atlas of Liver Metastases of Colorectal Cancer Reveals the Reprogramming of the Tumor Microenvironment in Response to Preoperative ChemotherapyDOI 10.21203/rs.3.rs-84915/v1
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