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Colorectal cancer metastases in the liver establish immunosuppressive spatial networking between tumor associated <i>SPP1</i> <sup>+</sup> macrophages and fibroblasts

2020-09-02

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Purpose</h4> The liver is the most frequent metastatic site for colorectal cancer ( CRC ). Its microenvironment is modified to provide a niche that allows CRC cell growth. This study focused on characterizing the cellular changes in the metastatic CRC ( mCRC ) liver tumor microenvironment ( TME ). <h4>Experimental Design</h4> We analyzed a series of microsatellite stable (MSS) mCRCs to...

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Literature Corpus work
6853de66-a989-5e1e-b941-bd03e72b8d00
DOI
10.1101/2020.09.01.273672
Open publication

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Colorectal cancer metastases in the liver establish immunosuppressive spatial networking between tumor associated <i>SPP1</i> <sup>+</sup> macrophages and fibroblastsDOI 10.1101/2020.09.01.273672
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