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Single-cell RNA-seq integration unveils liver vulnerability to tumor metastases: insights from myeloid cell characterization in pancreatic cancer liver metastatic

2023-11-29

Abstract excerpt

<h4>Background: </h4> The liver is the predominant metastatic site for diverse cancers, including pancreatic and colorectal cancers, etc. Liver metastasis increases cancer-related mortality, yet we have limited knowledge of the metastatic microenvironment to effectively target this process. Therefore, it is critical to understand the mechanisms underlying how the hepatic host tissues and immune cells differentiall...

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Literature Corpus work
3861a5a1-b6f6-5e7c-b641-e441aeb3bbed
DOI
10.21203/rs.3.rs-3668911/v1
Open publication

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Single-cell RNA-seq integration unveils liver vulnerability to tumor metastases: insights from myeloid cell characterization in pancreatic cancer liver metastaticDOI 10.21203/rs.3.rs-3668911/v1
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