Article
Estimation of genetic heritabilities of human traits in case-control studies.
Annals of human genetics - 1 May 2023
Hu Die, Chen Shuyue, Zhang Hong
Abstract excerpt
It is of great interest to detect missing heritability for human complex traits. Additive genetic effects (ADD), maternal genetic effects (MGE), and parent-of-origin effects (POE) play important roles in genetic mechanisms. Methods have been developed in the literature to analyze heritabilities due to ADD, POE, and MGE separately but not simultaneously. In this paper, a new model termed APM is proposed based on...
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