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Article

Emerging Roles of Growth Differentiation Factor 15 in Immunoregulation and Pathogenesis

1 Jan 2023

Abstract excerpt

Growth differentiation factor 15 (GDF-15) is a cytokine that is widely used as a biomarker for the severity of diverse disease states. It also has been shown to play a protective role after tissue injury and to promote a negative energy balance during obesity and diabetes. In addition to its metabolic effects, GDF-15 also regulates the host's immune responses to infectious and noninfectious diseases. GDF-15 can...

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PMID: 36542831
DOI: 10.4049/jimmunol.2200641

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