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Growth Differentiation Factor-15 in Immunity and Aging

9 Feb 2022

Abstract excerpt

Aging increases susceptibility to and severity of a variety of chronic and infectious diseases. Underlying this is dysfunction of the immune system, including chronic increases in low-grade inflammation (inflammaging) and age-related immunosuppression (immunosenescence). Growth differentiation factor-15 (GDF-15) is a stress-, infection-, and inflammation-induced cytokine which is increased in aging and suppresses...

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PMID: 35821815
DOI: 10.3389/fragi.2022.837575

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