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Article

Growth differentiation factor 15: A novel biomarker with high clinical potential

11 May 2019

Abstract excerpt

Initially considered as a macrophage inhibitor (macrophage inhibitory cytokine-1), growth differentiation factor 15 (GDF-15) has been identified as a pleiotropic protein that plays key roles in prenatal development, in inflammation, in the regulation of cellular responses to stress signals, and in tissue repair after acute injuries in adult life. Multiple studies have revealed that GDF-15, a distant member of the...

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PMID: 31076013
DOI: 10.1080/10408363.2019.1615034

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