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GDF-15 in Pulmonary and Critical Care Medicine

11 Jan 2019

Abstract excerpt

GDF-15 (growth differentiation factor 15) acts both as a stress-induced cytokine with diverse actions at different body sites and as a cell-autonomous regulator linked to cellular senescence and apoptosis. For multiple reasons, this divergent transforming growth factor-β molecular superfamily member should be better known to pulmonary researchers and clinicians. In ambulatory individuals, GDF-15 concentrations in...

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PMID: 30633545
DOI: 10.1165/rcmb.2018-0379tr

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