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Concise Review: Growth Differentiation Factor 15 in Pathology: A Clinical Role?

4 Nov 2013

Abstract excerpt

Growth differentiation factor 15 (GDF15) is a divergent member of the transforming growth factor β family discovered in a broad range of cells, as indicated by the diversity of its nomenclature. However, the only tissue that expresses a high amount of GDF15 in the physiologic state is placenta. GDF15 is easily detected in blood, and its concentration varies with age. In fact, increased blood concentration of...

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PMID: 24191265
DOI: 10.5966/sctm.2013-0055

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