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Article

GDF15 and Growth Control

27 Nov 2018

Abstract excerpt

Growth/differentiation factor-15 (GDF-15) is a distant member of the transforming growth factor β (TGF-β) superfamily and is widely expressed in multiple mammalian tissues. Its expression is highly regulated and is often induced in response to conditions associated with cellular stress. GDF15 serum levels have a strong association with many diseases, including inflammation, cancer, cardiovascular diseases, and...

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PMID: 30542297
DOI: 10.3389/fphys.2018.01712

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