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Article

Growth differentiation factor 15 and its role in carcinogenesis: an update

4 Jul 2019

Abstract excerpt

Growth differentiation factor-15 (GDF-15) is a novel cytokine secreted by a variety of cells like macrophages, adipocytes, normally expressed in high amounts by placenta. It is also highly expressed in multiple carcinomas like Colon, Breast, Pancreas, Liver, and Ovarian. Several reports on serum GDF-15 as a potential biomarker for diagnosis and prognosis of cancer are hampered by the lack of robust data, with...

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PMID: 31693861
DOI: 10.1080/08977194.2019.1685988

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