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GDF-15: A Multifunctional Modulator and Potential Therapeutic Target in Cancer

9 Apr 2019

Abstract excerpt

Various pathological processes are associated with the aberrant expression and function of cytokines, especially those belonging to the transforming growth factor-β (TGF-β) family. Nevertheless, the functions of members of the TGF-β family in cancer progression and therapy are still uncertain. Growth differentiation factor- 15, which exists in intracellular and extracellular forms, is classified as a divergent...

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PMID: 30947652
DOI: 10.2174/1381612825666190402101143

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