Article
HIV-1 resistance genotyping by ultra-deep sequencing and 6-month virological response to first-line treatment.
The Journal of antimicrobial chemotherapy - 1 Feb 2023
Raymond Stéphanie, Jeanne Nicolas, Nicot Florence, Dimeglio Chloé, Carcenac Romain, Harter Agnès, Ranger Noémie, Martin-Blondel Guillaume, Delobel Pierre, Izopet Jacques
Abstract excerpt
OBJECTIVES: To evaluate the routine use of the Sentosa ultra-deep sequencing (UDS) system for HIV-1 polymerase resistance genotyping in treatment-naïve individuals and to analyse the virological response (VR) to first-line antiretroviral treatment. METHODS: HIV drug resistance was determined on 2...
Topics
- Humans
- HIV-1
- Genotype
- HIV Infections
- Drug Resistance, Viral
- Anti-Retroviral Agents
- HIV Seropositivity
- HIV Integrase Inhibitors
- High-Throughput Nucleotide Sequencing
- Mutation
- Anti-HIV Agents