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Article

HIV-1 resistance genotyping by ultra-deep sequencing and 6-month virological response to first-line treatment.

The Journal of antimicrobial chemotherapy - 1 Feb 2023

Raymond Stéphanie, Jeanne Nicolas, Nicot Florence, Dimeglio Chloé, Carcenac Romain, Harter Agnès, Ranger Noémie, Martin-Blondel Guillaume, Delobel Pierre, Izopet Jacques

Abstract excerpt

OBJECTIVES: To evaluate the routine use of the Sentosa ultra-deep sequencing (UDS) system for HIV-1 polymerase resistance genotyping in treatment-naïve individuals and to analyse the virological response (VR) to first-line antiretroviral treatment. METHODS: HIV drug resistance was determined on 237 consecutive samples from treatment-naïve individuals using the Sentosa UDS platform with two mutation detection...

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Identifiers

PMID: 36449383
DOI: 10.1093/jac/dkac391

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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