Article
HIV-1 Drug Resistance Detected by Next-Generation Sequencing among ART-Naïve Individuals: A Systematic Review and Meta-Analysis.
Viruses - 2 Feb 2024
Ouyang Fei, Yuan Defu, Zhai Wenjing, Liu Shanshan, Zhou Ying, Yang Haitao
Abstract excerpt
BACKGROUND: There are an increasing number of articles focused on the prevalence and clinical impact of pretreatment HIV drug resistance (PDR) detected by Sanger sequencing (SGS). PDR may contribute to the increased likelihood of virologic failure and the emergence of new resistance mutations. As SGS is gradually replaced by next-generation sequencing (NGS), it is necessary to assess the levels of PDR using NGS...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
