Routine drug resistance testing in HIV-1 proviral DNA, using an automated next- generation sequencing assay.

doi:10.1016/j.jcv.2019.104207

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Article

Routine drug resistance testing in HIV-1 proviral DNA, using an automated next- generation sequencing assay.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Dec 2019

Alidjinou Enagnon Kazali, Coulon Pauline, Hallaert Christophe, Robineau Olivier, Meybeck Agnès, Huleux Thomas, Ajana Faiza, Hober Didier, Bocket Laurence

Abstract excerpt

BACKGROUND: HIV-1 DNA genotypic drug resistance testing is increasingly performed to guide treatment switching or simplification in controlled patients. The Sentosa NGS platform is a fully automated system marketed for drug resistance testing on HIV-1 RNA samples. OBJECTIVES: The aim of this stud...

Topics

Adult
Anti-HIV Agents
Drug Resistance, Viral
Female
Genotype
HIV Infections
HIV-1
High-Throughput Nucleotide Sequencing
Human Immunodeficiency Virus Proteins
Humans
Male
Microbial Sensitivity Tests
Middle Aged

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Proviruses

RNA, Viral

Retrospective Studies

Sequence Analysis, DNA

Source

Open in PubMed

Identifiers

PMID: 31707202
DOI: 10.1016/j.jcv.2019.104207

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-31707202-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.