Article
Routine drug resistance testing in HIV-1 proviral DNA, using an automated next- generation sequencing assay.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Dec 2019
Alidjinou Enagnon Kazali, Coulon Pauline, Hallaert Christophe, Robineau Olivier, Meybeck Agnès, Huleux Thomas, Ajana Faiza, Hober Didier, Bocket Laurence
Abstract excerpt
BACKGROUND: HIV-1 DNA genotypic drug resistance testing is increasingly performed to guide treatment switching or simplification in controlled patients. The Sentosa NGS platform is a fully automated system marketed for drug resistance testing on HIV-1 RNA samples. OBJECTIVES: The aim of this study was to evaluate this automated NGS solution for routine resistance genotypic resistance testing in proviral HIV-1...
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