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Article

Comparison of an In Vitro Diagnostic Next-Generation Sequencing Assay with Sanger Sequencing for HIV-1 Genotypic Resistance Testing.

Journal of clinical microbiology - 1 Jun 2018

Tzou Philip L, Ariyaratne Pramila, Varghese Vici, Lee Charlie, Rakhmanaliev Elian, Villy Carolin, Yee Meiqi, Tan Kevin, Michel Gerd, Pinsky Benjamin A, Shafer Robert W

Abstract excerpt

The ability of next-generation sequencing (NGS) technologies to detect low frequency HIV-1 drug resistance mutations (DRMs) not detected by dideoxynucleotide Sanger sequencing has potential advantages for improved patient outcomes. We compared the performance of an in vitro diagnostic (IVD) NGS assay, the Sentosa SQ HIV genotyping assay for HIV-1 genotypic resistance testing, with Sanger sequencing on 138...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29618499
DOI: 10.1128/JCM.00105-18
PMCID: PMC5971553

Genes

IVD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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