Article
Distinct frequency patterns of LILRB3 and LILRA6 allelic variants in Europeans.
Immunogenetics - 1 Jun 2023
Bashirova Arman A, Kasprzak Wojciech, O'hUigin Colm, Carrington Mary
Abstract excerpt
The leukocyte immunoglobulin-like receptor (LILR)B3 and LILRA6 genes encode homologous myeloid inhibitory and activating orphan receptors, respectively. Both genes exhibit a strikingly high level of polymorphism at the amino acid level and LILRA6 (but not LILRB3) displays copy number variation (CNV). Although multiple alleles have been reported for both genes, limited data is available on frequencies of these...
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